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DeCS
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Descriptor English:
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Aldo-Keto Reductase Family 1 Member C2
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Descriptor Spanish:
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miembro C2 de la familia 1 de las aldo-ceto reductasas
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Descriptor Portuguese:
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Membro C2 da Família 1 de alfa-Ceto Redutase
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Synonyms English:
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AKR1C2 Protein
Aldo Keto Reductase Family 1 Member C2
Dihydrodiol Dehydrogenase 2
Dihydrodiol Dehydrogenase Bile Acid Binding Protein
Dihydrodiol Dehydrogenase-Bile Acid Binding Protein
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Tree Number:
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D08.811.682.047.150.700.156.750
D08.811.682.047.820.284.875
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Definition English:
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Aldo-keto reductase that functions with 5-alpha and 5-beta-steroid reductases to convert steroid hormones into the 3-alpha or 5-alpha and 3-alpha or 5-beta-tetrahydrosteroid, including 5-ALPHA-DIHYDROTESTOSTERONE to ANDROSTANE-3,17-DIOL. It also binds to BILE ACIDS. Mutations in the AKR1C2 gene are associated with Type 8 DISORDER OF SEX DEVELOPMENT, 46,XY (SRXY8). |
History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57017
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Unique Identifier:
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D000074422
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Occurrence in VHL:
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Similar:
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DeCS
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